BDBM127872 US8791130, 1

SMILES: CNc1nc(Nc2ccc(cc2Cl)-c2nnn[nH]2)ncc1C(F)(F)F

InChI Key: InChIKey=MKTCKUJBFSZURA-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 127872   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Leucine-rich repeat serine/threonine-protein kinase 2 (LRRK2) (Homo sapiens (Human))	BDBM127872 (US8791130, 1) Show SMILES CNc1nc(Nc2ccc(cc2Cl)-c2nnn[nH]2)ncc1C(F)(F)F Show InChI InChI=1S/C13H10ClF3N8/c1-18-11-7(13(15,16)17)5-19-12(21-11)20-9-3-2-6(4-8(9)14)10-22-24-25-23-10/h2-5H,1H3,(H2,18,19,20,21)(H,22,23,24,25)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Genentech, Inc. US Patent					Assay Description This assay was used to determine a compound's potency in inhibiting activity of LRRK2 by determining, Kiapp, IC50, or percent inhibition values. ...				US Patent US8791130 (2014) BindingDB Entry DOI: 10.7270/Q2K9367R
					More data for this Ligand-Target Pair