BDBM127886 US8791130, 16

SMILES: CNc1nc(Nc2ccc(cc2OC)-c2cncn2C)ncc1Cl

InChI Key: InChIKey=XYFOLLFMNNEREC-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 127886   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Leucine-rich repeat serine/threonine-protein kinase 2 (LRRK2) (Homo sapiens (Human))	BDBM127886 (US8791130, 16) Show SMILES CNc1nc(Nc2ccc(cc2OC)-c2cncn2C)ncc1Cl Show InChI InChI=1S/C16H17ClN6O/c1-18-15-11(17)7-20-16(22-15)21-12-5-4-10(6-14(12)24-3)13-8-19-9-23(13)2/h4-9H,1-3H3,(H2,18,20,21,22)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	2	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Genentech, Inc. US Patent					Assay Description This assay was used to determine a compound's potency in inhibiting activity of LRRK2 by determining, Kiapp, IC50, or percent inhibition values. ...				US Patent US8791130 (2014) BindingDB Entry DOI: 10.7270/Q2K9367R
					More data for this Ligand-Target Pair