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SMILES: CNc1nc(Nc2cc(OC)c(cc2Cl)-c2cncn2C)ncc1C(F)(F)F

InChI Key: InChIKey=BPPFGYXCFXRQAM-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 127891   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Leucine-rich repeat serine/threonine-protein kinase 2


(Homo sapiens (Human))		BDBM127891
PNG
(US8791130, 21)
Show SMILES CNc1nc(Nc2cc(OC)c(cc2Cl)-c2cncn2C)ncc1C(F)(F)F
Show InChI InChI=1S/C17H16ClF3N6O/c1-22-15-10(17(19,20)21)6-24-16(26-15)25-12-5-14(28-3)9(4-11(12)18)13-7-23-8-27(13)2/h4-8H,1-3H3,(H2,22,24,25,26)
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Similars
US Patent
 3n/an/an/an/an/an/an/an/a



Genentech, Inc.

US Patent


Assay Description
This assay was used to determine a compound's potency in inhibiting activity of LRRK2 by determining, Kiapp, IC50, or percent inhibition values. ...

US Patent US8791130 (2014)


BindingDB Entry DOI: 10.7270/Q2K9367R
More data for this
Ligand-Target Pair