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SMILES: CNc1nc(Nc2cc3n(C)c(=O)n(C)c3cc2Cl)ncc1C(F)(F)F

InChI Key: InChIKey=JTBQSOITWIPAKO-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 128249   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Leucine-rich repeat serine/threonine-protein kinase 2


(Homo sapiens (Human))		BDBM128249
PNG
(US8796296, 4)
Show SMILES CNc1nc(Nc2cc3n(C)c(=O)n(C)c3cc2Cl)ncc1C(F)(F)F
Show InChI InChI=1S/C15H14ClF3N6O/c1-20-12-7(15(17,18)19)6-21-13(23-12)22-9-5-11-10(4-8(9)16)24(2)14(26)25(11)3/h4-6H,1-3H3,(H2,20,21,22,23)
PDB

KEGG

UniProtKB/SwissProt

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PC cid
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UniChem
US Patent
 2n/an/an/an/an/an/an/an/a



Genentech, Inc.

US Patent


Assay Description
his assay was used to determine a compound's potency in inhibiting activity of LRRK2 by determining, Kiapp, IC50, or percent inhibition values. In 38...

US Patent US8796296 (2014)


BindingDB Entry DOI: 10.7270/Q28W3C0R
More data for this
Ligand-Target Pair