BDBM128302 US8796284, 13
SMILES: CN(C)c1nc(nc(N)c1Br)-n1cccn1
InChI Key: InChIKey=XFEJMGUHELBLFD-UHFFFAOYSA-N
Data: 2 KI
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Adenosine receptor A2a (Homo sapiens (Human)) | BDBM128302 (US8796284, 13) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | 35 | -10.2 | n/a | n/a | n/a | n/a | n/a | n/a | 25 |
Palobiofarma, S.L. US Patent | Assay Description Competition assays were carried out by incubation of membranes from hA1 receptors transfected to CHO cells, [3H]-DPCPX as radioligand, buffer (HEPES ... | US Patent US8796284 (2014) BindingDB Entry DOI: 10.7270/Q2WM1C2Q | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Adenosine receptor A2a (Homo sapiens (Human)) | BDBM128302 (US8796284, 13) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | 50 | -10.4 | n/a | n/a | n/a | n/a | n/a | n/a | 37 |
Palobiofarma, S.L. US Patent | Assay Description hese assays were performed at adenosine receptors transfected using a cAMP enzymeimmunoassay kit (Amersham Biosciences). CHO-A2A cells were seeded (1... | US Patent US8796284 (2014) BindingDB Entry DOI: 10.7270/Q2WM1C2Q | |||||||||||
More data for this Ligand-Target Pair |