BDBM128311 US8796284, 93

SMILES: Nc1nc(nc(-c2nccs2)c1Br)-c1nccs1

InChI Key: InChIKey=HPPADDHIDIGPDJ-UHFFFAOYSA-N

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 128311   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Adenosine receptor A2a (Homo sapiens (Human))	BDBM128311 (US8796284, 93) Show SMILES Nc1nc(nc(-c2nccs2)c1Br)-c1nccs1 Show InChI InChI=1S/C10H6BrN5S2/c11-5-6(9-13-1-3-17-9)15-8(16-7(5)12)10-14-2-4-18-10/h1-4H,(H2,12,15,16)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	US Patent	1	-12.3	n/a	n/a	n/a	n/a	n/a	n/a	25
Palobiofarma, S.L. US Patent					Assay Description Competition assays were carried out by incubation of membranes from hA1 receptors transfected to CHO cells, [3H]-DPCPX as radioligand, buffer (HEPES ...				US Patent US8796284 (2014) BindingDB Entry DOI: 10.7270/Q2WM1C2Q
					More data for this Ligand-Target Pair
Adenosine receptor A2a (Homo sapiens (Human))	BDBM128311 (US8796284, 93) Show SMILES Nc1nc(nc(-c2nccs2)c1Br)-c1nccs1 Show InChI InChI=1S/C10H6BrN5S2/c11-5-6(9-13-1-3-17-9)15-8(16-7(5)12)10-14-2-4-18-10/h1-4H,(H2,12,15,16)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	US Patent	12	-11.2	n/a	n/a	n/a	n/a	n/a	n/a	37
Palobiofarma, S.L. US Patent					Assay Description hese assays were performed at adenosine receptors transfected using a cAMP enzymeimmunoassay kit (Amersham Biosciences). CHO-A2A cells were seeded (1...				US Patent US8796284 (2014) BindingDB Entry DOI: 10.7270/Q2WM1C2Q
					More data for this Ligand-Target Pair