BindingDB logo
myBDB logout

null

SMILES: CN(Cc1ccc(cc1)-c1nccnc1NS(=O)(=O)c1ccccc1C(F)(F)F)c1cccc(F)c1

InChI Key: InChIKey=RIHGKRHVIAPOEU-UHFFFAOYSA-N

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 128333   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Prostaglandin D2 receptor 2


(Homo sapiens (Human))		BDBM128333
PNG
(US8796280, 23)
Show SMILES CN(Cc1ccc(cc1)-c1nccnc1NS(=O)(=O)c1ccccc1C(F)(F)F)c1cccc(F)c1
Show InChI InChI=1S/C25H22F4N4O2S/c1-33(20-6-4-5-19(26)15-20)16-17-9-11-18(12-10-17)23-24(31-14-13-30-23)32-36(34,35)22-8-3-2-7-21(22)25(27,28)29/h2-15,36H,16H2,1H3,(H2,31,32,34,35)
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars
US Patent
 700 -8.39n/an/an/an/an/a7.425



Merck Serono, S.A.

US Patent


Assay Description
The compounds of the present invention inhibit the binding of PGD2 to its receptor CRTH2. The inhibitory activity can be investigated by a radioligan...

US Patent US8796280 (2014)


BindingDB Entry DOI: 10.7270/Q2RV0MCF
More data for this
Ligand-Target Pair