BDBM128993 US8802679, 69

SMILES: CN(Cc1cccc(c1)-c1cnc(nc1)N1CCOCC1)C(=O)CN

InChI Key: InChIKey=WLDMGLVKOTVKCB-UHFFFAOYSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 128993   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Membrane primary amine oxidase (Homo sapiens (Human))	BDBM128993 (US8802679, 69) Show SMILES CN(Cc1cccc(c1)-c1cnc(nc1)N1CCOCC1)C(=O)CN Show InChI InChI=1S/C18H23N5O2/c1-22(17(24)10-19)13-14-3-2-4-15(9-14)16-11-20-18(21-12-16)23-5-7-25-8-6-23/h2-4,9,11-12H,5-8,10,13,19H2,1H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	32	n/a	n/a	n/a	n/a	n/a	25
Astellas Pharma Inc. US Patent					Assay Description A human VAP-1 enzyme (SSAO) activity was measured by a radiochemistry-enzymatic assay using 14C-benzylamine as an artificial substrate. An enzyme sus...				US Patent US8802679 (2014) BindingDB Entry DOI: 10.7270/Q2M61HZD
					More data for this Ligand-Target Pair
Membrane primary amine oxidase (Homo sapiens (Human))	BDBM128993 (US8802679, 69) Show SMILES CN(Cc1cccc(c1)-c1cnc(nc1)N1CCOCC1)C(=O)CN Show InChI InChI=1S/C18H23N5O2/c1-22(17(24)10-19)13-14-3-2-4-15(9-14)16-11-20-18(21-12-16)23-5-7-25-8-6-23/h2-4,9,11-12H,5-8,10,13,19H2,1H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	31	n/a	n/a	n/a	n/a	n/a	n/a
Drug Discovery Research, Astellas Pharma Inc., 21 Miyukigaoka, Tsukuba, Ibaraki 305-8585, Japan. Electronic address: susumu.yamaki@astellas.com. Curated by ChEMBL					Assay Description Inhibition of human VAP-1 expressed in CHO cells preincubated for 20 mins followed by [14C]-benzylamine addition measured after 1 hr by scintillation...				Bioorg Med Chem 25: 6024-6038 (2017) Article DOI: 10.1016/j.bmc.2017.09.036 BindingDB Entry DOI: 10.7270/Q2B27XR3
					More data for this Ligand-Target Pair
Membrane primary amine oxidase (Rattus norvegicus (Rat))	BDBM128993 (US8802679, 69) Show SMILES CN(Cc1cccc(c1)-c1cnc(nc1)N1CCOCC1)C(=O)CN Show InChI InChI=1S/C18H23N5O2/c1-22(17(24)10-19)13-14-3-2-4-15(9-14)16-11-20-18(21-12-16)23-5-7-25-8-6-23/h2-4,9,11-12H,5-8,10,13,19H2,1H3	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	9.80	n/a	n/a	n/a	n/a	n/a	25
Astellas Pharma Inc. US Patent					Assay Description A rat VAP-enzyme 1 (SSAO) activity was measured by a radiochemistry-enzymatic assay using 14C-benzylamine as an artificial substrate. An enzyme suspe...				US Patent US8802679 (2014) BindingDB Entry DOI: 10.7270/Q2M61HZD
					More data for this Ligand-Target Pair