BDBM129195 US8802674, 302

SMILES: CCNc1nc(Nc2ccc(cc2OC)C(=O)N(C)CCOC)ncc1C(F)(F)F

InChI Key: InChIKey=ZXNKPBAJMDKTFK-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 129195   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Leucine-rich repeat serine/threonine-protein kinase 2 (LRRK2) (Homo sapiens (Human))	BDBM129195 (US8802674, 302) Show SMILES CCNc1nc(Nc2ccc(cc2OC)C(=O)N(C)CCOC)ncc1C(F)(F)F Show InChI InChI=1S/C19H24F3N5O3/c1-5-23-16-13(19(20,21)22)11-24-18(26-16)25-14-7-6-12(10-15(14)30-4)17(28)27(2)8-9-29-3/h6-7,10-11H,5,8-9H2,1-4H3,(H2,23,24,25,26)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	2.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Genentech, Inc. US Patent					Assay Description This assay was used to determine a compound's potency in inhibiting activity of LRRK2 by determining, Kiapp, IC50, or percent inhibition values. ...				US Patent US8802674 (2014) BindingDB Entry DOI: 10.7270/Q2GF0S6N
					More data for this Ligand-Target Pair