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SMILES: CC(C)Cn1cc(-c2nc(no2)-c2cc(F)ccc2F)c(n1)-c1ccccc1

InChI Key: InChIKey=NABZTAHJRWFIRJ-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 129574   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Sphingosine 1-phosphate receptor 1


(Homo sapiens (Human))		BDBM129574
PNG
(US8802663, 8)
Show SMILES CC(C)Cn1cc(-c2nc(no2)-c2cc(F)ccc2F)c(n1)-c1ccccc1
Show InChI InChI=1S/C21H18F2N4O/c1-13(2)11-27-12-17(19(25-27)14-6-4-3-5-7-14)21-24-20(26-28-21)16-10-15(22)8-9-18(16)23/h3-10,12-13H,11H2,1-2H3
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Similars
US Patent
 3 -10.8n/an/an/an/an/a7.44



Merck Serono SA

US Patent


Assay Description
Receptor binding assay: Membranes were prepared from CHO cells expressing S1P1 or S1P3 for use in ligand and 355-GTPgammaS binding studies. Cells wer...

US Patent US8802663 (2014)


BindingDB Entry DOI: 10.7270/Q2ZC81K5
More data for this
Ligand-Target Pair