BDBM129635 US8815934, No. 113

SMILES: Cc1c(-c2ccc(O)cc2)n(Cc2ccc(OCCN3CCC(O)CC3)cc2)c2ccc(O)cc12

InChI Key: InChIKey=GZGPRSXNTFCESG-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 129635   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Estrogen receptor (Homo sapiens (Human))	BDBM129635 (US8815934, No. 113) Show SMILES Cc1c(-c2ccc(O)cc2)n(Cc2ccc(OCCN3CCC(O)CC3)cc2)c2ccc(O)cc12 Show InChI InChI=1S/C29H32N2O4/c1-20-27-18-25(34)8-11-28(27)31(29(20)22-4-6-23(32)7-5-22)19-21-2-9-26(10-3-21)35-17-16-30-14-12-24(33)13-15-30/h2-11,18,24,32-34H,12-17,19H2,1H3	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	47	n/a	n/a	n/a	n/a	n/a	4
Wyeth LLC US Patent					Assay Description The competition assay was performed in a 96-well plate (polystyrene*) which binds <2.0% of the total input [3H]-17beta-estradiol and each data point ...				US Patent US8815934 (2014) BindingDB Entry DOI: 10.7270/Q2PZ57H0
					More data for this Ligand-Target Pair