BDBM129718 US8802672, 6
SMILES: CCNc1nc(Cl)c(Cl)c(n1)N1CCN(CCC2CCC(CC2)NC(C)=O)CC1
InChI Key: InChIKey=NTEASVXKHYIMOF-UHFFFAOYSA-N
Data: 3 KI
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
D(3) dopamine receptor (Rattus norvegicus (Rat)) | BDBM129718 (US8802672, 6) | KEGG UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | 2 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Richter Gedeon Nyrt. US Patent | Assay Description Binding assays were carried out on rat recombinant D3 receptors (Perkin-Elmer, Cat. No. 6110139) expressed in Sf9 cells using [3H]spiperone (0.44-1.4... | US Patent US8802672 (2014) BindingDB Entry DOI: 10.7270/Q2FF3R1T | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(2) dopamine receptor (Rattus norvegicus (rat)) | BDBM129718 (US8802672, 6) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | 35 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Richter Gedeon Nyrt. US Patent | Assay Description D2 receptor binding was determined as described by Creese et al. (Eur. J. Pharmacol., 60:55-66, 1979) on rat brain striatal membrane preparation usin... | US Patent US8802672 (2014) BindingDB Entry DOI: 10.7270/Q2FF3R1T | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha-1A adrenergic receptor (Rattus norvegicus (Rat)) | BDBM129718 (US8802672, 6) | KEGG UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | >1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Richter Gedeon Nyrt. US Patent | Assay Description Alpha-1 receptor binding studies were performed according to the methods described by Greengrass and Bremner (Eur. J. Pharmacol., 55:323-326, 1979) o... | US Patent US8802672 (2014) BindingDB Entry DOI: 10.7270/Q2FF3R1T | |||||||||||
More data for this Ligand-Target Pair |