null

SMILES: CNc1nc(Cl)c(Cl)c(n1)N1CCN(CCC2CCC(CC2)NC(=O)N2CCOCC2)CC1

InChI Key: InChIKey=AXVHZOULLRVZMO-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 129719   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
D(3) dopamine receptor (Rattus norvegicus (Rat))	BDBM129719 (US8802672, 7) Show SMILES CNc1nc(Cl)c(Cl)c(n1)N1CCN(CCC2CCC(CC2)NC(=O)N2CCOCC2)CC1 |(-4.53,8.84,;-3.2,9.61,;-1.86,8.84,;-.53,9.61,;.81,8.84,;2.14,9.61,;.81,7.3,;2.14,6.53,;-.53,6.53,;-1.86,7.3,;-.53,4.99,;-1.86,4.22,;-1.86,2.68,;-.53,1.91,;-.53,.37,;.81,-.4,;.81,-1.94,;-.53,-2.71,;-.53,-4.25,;.81,-5.02,;2.14,-4.25,;2.14,-2.71,;.81,-6.56,;2.14,-7.33,;3.47,-6.56,;2.14,-8.87,;3.47,-9.64,;3.47,-11.18,;2.14,-11.95,;.81,-11.18,;.81,-9.64,;.81,2.68,;.81,4.22,)| Show InChI InChI=1S/C22H35Cl2N7O2/c1-25-21-27-19(24)18(23)20(28-21)30-10-8-29(9-11-30)7-6-16-2-4-17(5-3-16)26-22(32)31-12-14-33-15-13-31/h16-17H,2-15H2,1H3,(H,26,32)(H,25,27,28)	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	2	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Richter Gedeon Nyrt. US Patent					Assay Description Binding assays were carried out on rat recombinant D3 receptors (Perkin-Elmer, Cat. No. 6110139) expressed in Sf9 cells using [3H]spiperone (0.44-1.4...				US Patent US8802672 (2014) BindingDB Entry DOI: 10.7270/Q2FF3R1T
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM129719 (US8802672, 7) Show SMILES CNc1nc(Cl)c(Cl)c(n1)N1CCN(CCC2CCC(CC2)NC(=O)N2CCOCC2)CC1 |(-4.53,8.84,;-3.2,9.61,;-1.86,8.84,;-.53,9.61,;.81,8.84,;2.14,9.61,;.81,7.3,;2.14,6.53,;-.53,6.53,;-1.86,7.3,;-.53,4.99,;-1.86,4.22,;-1.86,2.68,;-.53,1.91,;-.53,.37,;.81,-.4,;.81,-1.94,;-.53,-2.71,;-.53,-4.25,;.81,-5.02,;2.14,-4.25,;2.14,-2.71,;.81,-6.56,;2.14,-7.33,;3.47,-6.56,;2.14,-8.87,;3.47,-9.64,;3.47,-11.18,;2.14,-11.95,;.81,-11.18,;.81,-9.64,;.81,2.68,;.81,4.22,)| Show InChI InChI=1S/C22H35Cl2N7O2/c1-25-21-27-19(24)18(23)20(28-21)30-10-8-29(9-11-30)7-6-16-2-4-17(5-3-16)26-22(32)31-12-14-33-15-13-31/h16-17H,2-15H2,1H3,(H,26,32)(H,25,27,28)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Richter Gedeon Nyrt. US Patent					Assay Description D2 receptor binding was determined as described by Creese et al. (Eur. J. Pharmacol., 60:55-66, 1979) on rat brain striatal membrane preparation usin...				US Patent US8802672 (2014) BindingDB Entry DOI: 10.7270/Q2FF3R1T
					More data for this Ligand-Target Pair
Alpha-1A adrenergic receptor (Rattus norvegicus (Rat))	BDBM129719 (US8802672, 7) Show SMILES CNc1nc(Cl)c(Cl)c(n1)N1CCN(CCC2CCC(CC2)NC(=O)N2CCOCC2)CC1 |(-4.53,8.84,;-3.2,9.61,;-1.86,8.84,;-.53,9.61,;.81,8.84,;2.14,9.61,;.81,7.3,;2.14,6.53,;-.53,6.53,;-1.86,7.3,;-.53,4.99,;-1.86,4.22,;-1.86,2.68,;-.53,1.91,;-.53,.37,;.81,-.4,;.81,-1.94,;-.53,-2.71,;-.53,-4.25,;.81,-5.02,;2.14,-4.25,;2.14,-2.71,;.81,-6.56,;2.14,-7.33,;3.47,-6.56,;2.14,-8.87,;3.47,-9.64,;3.47,-11.18,;2.14,-11.95,;.81,-11.18,;.81,-9.64,;.81,2.68,;.81,4.22,)| Show InChI InChI=1S/C22H35Cl2N7O2/c1-25-21-27-19(24)18(23)20(28-21)30-10-8-29(9-11-30)7-6-16-2-4-17(5-3-16)26-22(32)31-12-14-33-15-13-31/h16-17H,2-15H2,1H3,(H,26,32)(H,25,27,28)	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Richter Gedeon Nyrt. US Patent					Assay Description Alpha-1 receptor binding studies were performed according to the methods described by Greengrass and Bremner (Eur. J. Pharmacol., 55:323-326, 1979) o...				US Patent US8802672 (2014) BindingDB Entry DOI: 10.7270/Q2FF3R1T
					More data for this Ligand-Target Pair