BDBM130222 US8815854, 11

SMILES: NC1(CCC1)c1ccc(cc1)-n1c(nc2ccc(nc12)-c1cccc(c1)N1CCOCC1)C1CC1

InChI Key: InChIKey=UUDGMWJXXJRQBJ-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 130222   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
RAC-alpha serine/threonine-protein kinase (Homo sapiens (Human))	BDBM130222 (US8815854, 11) Show SMILES NC1(CCC1)c1ccc(cc1)-n1c(nc2ccc(nc12)-c1cccc(c1)N1CCOCC1)C1CC1 Show InChI InChI=1S/C29H31N5O/c30-29(13-2-14-29)22-7-9-23(10-8-22)34-27(20-5-6-20)32-26-12-11-25(31-28(26)34)21-3-1-4-24(19-21)33-15-17-35-18-16-33/h1,3-4,7-12,19-20H,2,5-6,13-18,30H2	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	1.99	n/a	n/a	n/a	n/a	8.0	n/a
ArQule, Inc. US Patent					Assay Description AKT1 activity was assayed using the GSK3-derived biotinylated peptide substrate, crosstide (biotin-GRPRTSSFAEG), and AlphaScreen (Amplified Luminesce...				US Patent US8815854 (2014) BindingDB Entry DOI: 10.7270/Q2J67FMR
					More data for this Ligand-Target Pair