BDBM130370 US8822534, Example 15-1::US8993631, 12-1

SMILES: OC(=O)C[C@@H](Cc1ccc(cc1)-c1cccc(Cl)c1)NC(=O)c1nn[nH]n1

InChI Key: InChIKey=AGMDDGBZRAZZDC-OAHLLOKOSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 130370   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Neutral endopeptidase (NEP) (Homo sapiens (Human))	BDBM130370 (US8822534, Example 15-1 | US8993631, 12-1) Show SMILES OC(=O)C[C@@H](Cc1ccc(cc1)-c1cccc(Cl)c1)NC(=O)c1nn[nH]n1 Show InChI InChI=1S/C18H16ClN5O3/c19-14-3-1-2-13(9-14)12-6-4-11(5-7-12)8-15(10-16(25)26)20-18(27)17-21-23-24-22-17/h1-7,9,15H,8,10H2,(H,20,27)(H,25,26)(H,21,22,23,24)/t15-/m1/s1	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	1.20	n/a	n/a	n/a	n/a	7.4	25
Novartis AG US Patent					Assay Description Recombinant human neutral endopeptidase (expressed in insect cells and purified using standard methods, final concentration 7 μM) is pre-incubat...				US Patent US8993631 (2015) BindingDB Entry DOI: 10.7270/Q20C4THK
					More data for this Ligand-Target Pair
Neutral endopeptidase (NEP) (Homo sapiens (Human))	BDBM130370 (US8822534, Example 15-1 | US8993631, 12-1) Show SMILES OC(=O)C[C@@H](Cc1ccc(cc1)-c1cccc(Cl)c1)NC(=O)c1nn[nH]n1 Show InChI InChI=1S/C18H16ClN5O3/c19-14-3-1-2-13(9-14)12-6-4-11(5-7-12)8-15(10-16(25)26)20-18(27)17-21-23-24-22-17/h1-7,9,15H,8,10H2,(H,20,27)(H,25,26)(H,21,22,23,24)/t15-/m1/s1	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	1.20	n/a	n/a	n/a	n/a	7.4	25
Novartis AG US Patent					Assay Description Recombinant human neutral endopeptidase (expressed in insect cells and purified using standard methods, final concentration 7 μM) is pre-incubat...				US Patent US8822534 (2014) BindingDB Entry DOI: 10.7270/Q2513WW2
					More data for this Ligand-Target Pair