BDBM130666 US8822447, 180::US9771375, Example 180
SMILES: CSc1nn(-c2ccccc2C)c2cc(ccc12)C1=CCNCC1
InChI Key: InChIKey=CXRDFIBCRNVOFH-UHFFFAOYSA-N
Data: 3 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Ketohexokinase (KHK) Isoform C (Homo sapiens (Human)) | BDBM130666 (US8822447, 180 | US9771375, Example 180) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | 25 |
Janssen Pharmaceutica NV US Patent | Assay Description An enzymatic assay was developed to measure KHK-mediated conversion of D-fructose to Fructose-1-P (F-1-P) using High Throughput Mass Spectroscopy (HT... | US Patent US8822447 (2014) BindingDB Entry DOI: 10.7270/Q2M0443Q | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Ketohexokinase (KHK) Isoform C (Homo sapiens (Human)) | BDBM130666 (US8822447, 180 | US9771375, Example 180) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Janssen Pharmaceutica NV US Patent | Assay Description An enzymatic assay was developed to measure KHK-mediated conversion of D-fructose to Fructose-1-P (F-1-P) using High Throughput Mass Spectroscopy (HT... | US Patent US9771375 (2017) BindingDB Entry DOI: 10.7270/Q20R9RJW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Ketohexokinase (KHK) Isoform C (Homo sapiens (Human)) | BDBM130666 (US8822447, 180 | US9771375, Example 180) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 40 | n/a | n/a | n/a | n/a | n/a | n/a |
Janssen Pharmaceutica NV US Patent | Assay Description An enzymatic assay was developed to measure KHK-mediated conversion of D-fructose to Fructose-1-P (F-1-P) using High Throughput Mass Spectroscopy (HT... | US Patent US9771375 (2017) BindingDB Entry DOI: 10.7270/Q20R9RJW | |||||||||||
More data for this Ligand-Target Pair |