BDBM130670 US8829200, 3

SMILES: CC(C)(C)n1c(nc2cc(ccc12)-c1cnc(N)nc1)-c1ccccc1C(=O)Nc1ccncc1

InChI Key: InChIKey=TXGKTJNTZQOYEI-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 130670   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-lipoxygenase/FLAP (Homo sapiens (Human))	BDBM130670 (US8829200, 3) Show SMILES CC(C)(C)n1c(nc2cc(ccc12)-c1cnc(N)nc1)-c1ccccc1C(=O)Nc1ccncc1 Show InChI InChI=1S/C27H25N7O/c1-27(2,3)34-23-9-8-17(18-15-30-26(28)31-16-18)14-22(23)33-24(34)20-6-4-5-7-21(20)25(35)32-19-10-12-29-13-11-19/h4-16H,1-3H3,(H2,28,30,31)(H,29,32,35)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	0.910	n/a	n/a	n/a	n/a	n/a	7.5
Boehringer Ingelheim International GmbH US Patent					Assay Description Compounds are assessed for the ability to bind to FLAP in a binding assay that measures compound-specific displacement of an iodinated (125I) FLAP in...				US Patent US8829200 (2014) BindingDB Entry DOI: 10.7270/Q2G73CDF
					More data for this Ligand-Target Pair