BDBM130700 US8829200, 20

SMILES: CC(C)(C)n1c(nc2cc(ccc12)-c1cnc(N)nc1)-c1ccccc1C(=O)Nc1ccccn1

InChI Key: InChIKey=ILLHEVNYTPWDPF-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 130700   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-lipoxygenase/FLAP (Homo sapiens (Human))	BDBM130700 (US8829200, 20) Show SMILES CC(C)(C)n1c(nc2cc(ccc12)-c1cnc(N)nc1)-c1ccccc1C(=O)Nc1ccccn1 Show InChI InChI=1S/C27H25N7O/c1-27(2,3)34-22-12-11-17(18-15-30-26(28)31-16-18)14-21(22)32-24(34)19-8-4-5-9-20(19)25(35)33-23-10-6-7-13-29-23/h4-16H,1-3H3,(H2,28,30,31)(H,29,33,35)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	2.20	n/a	n/a	n/a	n/a	n/a	7.5
Boehringer Ingelheim International GmbH US Patent					Assay Description Compounds are assessed for the ability to bind to FLAP in a binding assay that measures compound-specific displacement of an iodinated (125I) FLAP in...				US Patent US8829200 (2014) BindingDB Entry DOI: 10.7270/Q2G73CDF
					More data for this Ligand-Target Pair