BDBM130943 US8829190, 121

SMILES: COc1ccc(C(=O)Cc2ccnc3ccccc23)n2nc(nc12)C1(CO)CC1

InChI Key: InChIKey=STKNBMVQBHIVNK-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 130943   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cAMP-specific 3',5'-cyclic phosphodiesterase 4A (Homo sapiens (Human))	BDBM130943 (US8829190, 121) Show SMILES COc1ccc(C(=O)Cc2ccnc3ccccc23)n2nc(nc12)C1(CO)CC1 Show InChI InChI=1S/C22H20N4O3/c1-29-19-7-6-17(26-20(19)24-21(25-26)22(13-27)9-10-22)18(28)12-14-8-11-23-16-5-3-2-4-15(14)16/h2-8,11,27H,9-10,12-13H2,1H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	3.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
Leo Pharma A/S US Patent					Assay Description Human recombinant PDE4 (Gene bank accession no NM006203) was incubated for 1 hour with the test compound at concentrations up to 10 μM, with cAM...				US Patent US8829190 (2014) BindingDB Entry DOI: 10.7270/Q2Z89B3Z
					More data for this Ligand-Target Pair