BDBM131015 US8829000, 189

SMILES: OC(=O)\C=C\c1ccc2n1c1ccc(cc1[nH]c2=O)C(F)(F)F

InChI Key: InChIKey=ZKGGCZGXEZKASH-ZZXKWVIFSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 131015   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cGMP-specific 3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM131015 (US8829000, 189) Show SMILES OC(=O)\C=C\c1ccc2n1c1ccc(cc1[nH]c2=O)C(F)(F)F Show InChI InChI=1S/C15H9F3N2O3/c16-15(17,18)8-1-4-11-10(7-8)19-14(23)12-5-2-9(20(11)12)3-6-13(21)22/h1-7H,(H,19,23)(H,21,22)/b6-3+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	4.56E+3	n/a	n/a	n/a	n/a	n/a	30
ASKA Pharmaceutical Co., Ltd. US Patent					Assay Description By a method similar to the measurement of PDE9-inhibiting activity, PDE5-inhibiting activity of each of the test compounds was measured, percent inhi...				US Patent US8829000 (2014) BindingDB Entry DOI: 10.7270/Q2K072ZX
					More data for this Ligand-Target Pair
Phosphodiesterase 9A (Homo sapiens (Human))	BDBM131015 (US8829000, 189) Show SMILES OC(=O)\C=C\c1ccc2n1c1ccc(cc1[nH]c2=O)C(F)(F)F Show InChI InChI=1S/C15H9F3N2O3/c16-15(17,18)8-1-4-11-10(7-8)19-14(23)12-5-2-9(20(11)12)3-6-13(21)22/h1-7H,(H,19,23)(H,21,22)/b6-3+	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	8	n/a	n/a	n/a	n/a	n/a	30
ASKA Pharmaceutical Co., Ltd. US Patent					Assay Description To 150 uL of buffer B (70 mmol/L Tris-HCl, pH7.5, 16.7 mmol/L MgCl2, 33.3 nmol/L [3H]-cGMP) solution containing [3H]-cGMP (specific activity=244.2 GB...				US Patent US8829000 (2014) BindingDB Entry DOI: 10.7270/Q2K072ZX
					More data for this Ligand-Target Pair