BDBM131084 US8835472, 2.17

SMILES: CC(C)COc1ccc(cc1)C#Cc1ccc(CC(C)NC(C)=O)cc1

InChI Key: InChIKey=TVCOCLDTETZHAV-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 131084   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Acetyl-CoA carboxylase 2 (ACC2) (Homo sapiens (Human))	BDBM131084 (US8835472, 2.17) Show SMILES CC(C)COc1ccc(cc1)C#Cc1ccc(CC(C)NC(C)=O)cc1 Show InChI InChI=1S/C23H27NO2/c1-17(2)16-26-23-13-11-21(12-14-23)6-5-20-7-9-22(10-8-20)15-18(3)24-19(4)25/h7-14,17-18H,15-16H2,1-4H3,(H,24,25)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	110	n/a	n/a	n/a	n/a	7.5	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description Malonyl CoA formation by acetyl CoA carboxylases is stoichometrically linked to the consumption of ATP. ACC2 activity is measured in a NADH-linked ki...				US Patent US8835472 (2014) BindingDB Entry DOI: 10.7270/Q25T3J6W
					More data for this Ligand-Target Pair