BDBM131102 US8835472, 2.35

SMILES: CCCOc1ccc(cn1)C#Cc1ccc(cc1)C(C)(C)CNC(C)=O

InChI Key: InChIKey=ILDHIWVTYZPSBR-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 131102   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Acetyl-CoA carboxylase 2 (ACC2) (Homo sapiens (Human))	BDBM131102 (US8835472, 2.35) Show SMILES CCCOc1ccc(cn1)C#Cc1ccc(cc1)C(C)(C)CNC(C)=O Show InChI InChI=1S/C22H26N2O2/c1-5-14-26-21-13-10-19(15-23-21)7-6-18-8-11-20(12-9-18)22(3,4)16-24-17(2)25/h8-13,15H,5,14,16H2,1-4H3,(H,24,25)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	130	n/a	n/a	n/a	n/a	7.5	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description Malonyl CoA formation by acetyl CoA carboxylases is stoichometrically linked to the consumption of ATP. ACC2 activity is measured in a NADH-linked ki...				US Patent US8835472 (2014) BindingDB Entry DOI: 10.7270/Q25T3J6W
					More data for this Ligand-Target Pair