BDBM131160 US8835472, 2.93

SMILES: CCCOc1ccc(C#Cc2ccc(CC(C)NC(C)=O)cc2)c(Cl)c1

InChI Key: InChIKey=HECXXBZPWALCGF-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 131160   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Acetyl-CoA carboxylase 2 (ACC2) (Homo sapiens (Human))	BDBM131160 (US8835472, 2.93) Show SMILES CCCOc1ccc(C#Cc2ccc(CC(C)NC(C)=O)cc2)c(Cl)c1 Show InChI InChI=1S/C22H24ClNO2/c1-4-13-26-21-12-11-20(22(23)15-21)10-9-18-5-7-19(8-6-18)14-16(2)24-17(3)25/h5-8,11-12,15-16H,4,13-14H2,1-3H3,(H,24,25)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	80	n/a	n/a	n/a	n/a	7.5	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description Malonyl CoA formation by acetyl CoA carboxylases is stoichometrically linked to the consumption of ATP. ACC2 activity is measured in a NADH-linked ki...				US Patent US8835472 (2014) BindingDB Entry DOI: 10.7270/Q25T3J6W
					More data for this Ligand-Target Pair