BDBM131259 US8835472, 4.67

SMILES: CCOc1ccc(cc1)C#Cc1ccc(CC(C)NC(=O)c2cncs2)cc1

InChI Key: InChIKey=DAXAPMSISSWGRN-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 131259   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Acetyl-CoA carboxylase 2 (ACC2) (Homo sapiens (Human))	BDBM131259 (US8835472, 4.67) Show SMILES CCOc1ccc(cc1)C#Cc1ccc(CC(C)NC(=O)c2cncs2)cc1 Show InChI InChI=1S/C23H22N2O2S/c1-3-27-21-12-10-19(11-13-21)5-4-18-6-8-20(9-7-18)14-17(2)25-23(26)22-15-24-16-28-22/h6-13,15-17H,3,14H2,1-2H3,(H,25,26)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	70	n/a	n/a	n/a	n/a	7.5	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description Malonyl CoA formation by acetyl CoA carboxylases is stoichometrically linked to the consumption of ATP. ACC2 activity is measured in a NADH-linked ki...				US Patent US8835472 (2014) BindingDB Entry DOI: 10.7270/Q25T3J6W
					More data for this Ligand-Target Pair