BDBM131354 US8835472, 9.21

SMILES: CC(Cc1ccc(cc1)C#Cc1ccc(OCCC2CC2)cc1)NC(C)=O

InChI Key: InChIKey=AXUWCRKFFXZXPO-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 131354   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Acetyl-CoA carboxylase 2 (ACC2) (Homo sapiens (Human))	BDBM131354 (US8835472, 9.21) Show SMILES CC(Cc1ccc(cc1)C#Cc1ccc(OCCC2CC2)cc1)NC(C)=O Show InChI InChI=1S/C24H27NO2/c1-18(25-19(2)26)17-23-9-7-20(8-10-23)3-4-21-11-13-24(14-12-21)27-16-15-22-5-6-22/h7-14,18,22H,5-6,15-17H2,1-2H3,(H,25,26)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	60	n/a	n/a	n/a	n/a	7.5	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description Malonyl CoA formation by acetyl CoA carboxylases is stoichometrically linked to the consumption of ATP. ACC2 activity is measured in a NADH-linked ki...				US Patent US8835472 (2014) BindingDB Entry DOI: 10.7270/Q25T3J6W
					More data for this Ligand-Target Pair