BDBM131373 US8835472, 9.40

SMILES: CC(Cc1ccc(cc1)C#Cc1ccc(OCC2CC2(F)F)cc1)NC(C)=O

InChI Key: InChIKey=NYIYRBUGULPMQC-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 131373   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Acetyl-CoA carboxylase 2 (ACC2) (Homo sapiens (Human))	BDBM131373 (US8835472, 9.40) Show SMILES CC(Cc1ccc(cc1)C#Cc1ccc(OCC2CC2(F)F)cc1)NC(C)=O Show InChI InChI=1S/C23H23F2NO2/c1-16(26-17(2)27)13-20-7-5-18(6-8-20)3-4-19-9-11-22(12-10-19)28-15-21-14-23(21,24)25/h5-12,16,21H,13-15H2,1-2H3,(H,26,27)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	50	n/a	n/a	n/a	n/a	7.5	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description Malonyl CoA formation by acetyl CoA carboxylases is stoichometrically linked to the consumption of ATP. ACC2 activity is measured in a NADH-linked ki...				US Patent US8835472 (2014) BindingDB Entry DOI: 10.7270/Q25T3J6W
					More data for this Ligand-Target Pair