BDBM131439 US8835472, 12.12

SMILES: CC(Cc1ccc(cc1)C#Cc1cnc(OC2CCC2)nc1)NC(C)=O

InChI Key: InChIKey=QXRPLPLYHXLNFU-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 131439   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Acetyl-CoA carboxylase 2 (ACC2) (Homo sapiens (Human))	BDBM131439 (US8835472, 12.12) Show SMILES CC(Cc1ccc(cc1)C#Cc1cnc(OC2CCC2)nc1)NC(C)=O Show InChI InChI=1S/C21H23N3O2/c1-15(24-16(2)25)12-18-9-6-17(7-10-18)8-11-19-13-22-21(23-14-19)26-20-4-3-5-20/h6-7,9-10,13-15,20H,3-5,12H2,1-2H3,(H,24,25)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	90	n/a	n/a	n/a	n/a	7.5	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description Malonyl CoA formation by acetyl CoA carboxylases is stoichometrically linked to the consumption of ATP. ACC2 activity is measured in a NADH-linked ki...				US Patent US8835472 (2014) BindingDB Entry DOI: 10.7270/Q25T3J6W
					More data for this Ligand-Target Pair