BDBM131638 US8835472, 14.47

SMILES: CC(Cc1ccc(cc1)C#Cc1ccc(OC2CCCC2)cc1)NC(=O)C1CC1

InChI Key: InChIKey=GGAHXYRVDHVAMQ-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 131638   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Acetyl-CoA carboxylase 2 (ACC2) (Homo sapiens (Human))	BDBM131638 (US8835472, 14.47) Show SMILES CC(Cc1ccc(cc1)C#Cc1ccc(OC2CCCC2)cc1)NC(=O)C1CC1 Show InChI InChI=1S/C26H29NO2/c1-19(27-26(28)23-14-15-23)18-22-10-8-20(9-11-22)6-7-21-12-16-25(17-13-21)29-24-4-2-3-5-24/h8-13,16-17,19,23-24H,2-5,14-15,18H2,1H3,(H,27,28)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	80	n/a	n/a	n/a	n/a	7.5	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description Malonyl CoA formation by acetyl CoA carboxylases is stoichometrically linked to the consumption of ATP. ACC2 activity is measured in a NADH-linked ki...				US Patent US8835472 (2014) BindingDB Entry DOI: 10.7270/Q25T3J6W
					More data for this Ligand-Target Pair