BDBM131646 US8835472, 14.55

SMILES: CC(Cc1ccc(cc1)C#Cc1ccc2OCC(C)(C)COc2c1)NC(C)=O

InChI Key: InChIKey=FFMOWMAHSQRGHP-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 131646   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Acetyl-CoA carboxylase 2 (ACC2) (Homo sapiens (Human))	BDBM131646 (US8835472, 14.55) Show SMILES CC(Cc1ccc(cc1)C#Cc1ccc2OCC(C)(C)COc2c1)NC(C)=O Show InChI InChI=1S/C24H27NO3/c1-17(25-18(2)26)13-20-8-5-19(6-9-20)7-10-21-11-12-22-23(14-21)28-16-24(3,4)15-27-22/h5-6,8-9,11-12,14,17H,13,15-16H2,1-4H3,(H,25,26)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	120	n/a	n/a	n/a	n/a	7.5	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description Malonyl CoA formation by acetyl CoA carboxylases is stoichometrically linked to the consumption of ATP. ACC2 activity is measured in a NADH-linked ki...				US Patent US8835472 (2014) BindingDB Entry DOI: 10.7270/Q25T3J6W
					More data for this Ligand-Target Pair