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SMILES: COc1cc(ccc1F)N1CCN(C1=O)c1cnccc1C

InChI Key: InChIKey=NINSHVGQARQIAC-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 132140   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Steroid 17-alpha-hydroxylase/17,20 lyase


(Homo sapiens (Human))		BDBM132140
PNG
(USRE45173, 74A)
Show SMILES COc1cc(ccc1F)N1CCN(C1=O)c1cnccc1C
Show InChI InChI=1S/C16H16FN3O2/c1-11-5-6-18-10-14(11)20-8-7-19(16(20)21)12-3-4-13(17)15(9-12)22-2/h3-6,9-10H,7-8H2,1-2H3
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Similars
US Patent
n/an/a 76n/an/an/an/an/an/a



Novartis AG

US Patent


Assay Description
Cytochrome P450, 17-20 lyase (CYP17-lyase) assay development using recombinant human CYP17 enzyme and 17-alpha -hydroxy pregnenolone [21-3H] as the s...

US Patent USRE45173 (2014)


BindingDB Entry DOI: 10.7270/Q2MW2FT2
More data for this
Ligand-Target Pair