BDBM132204 USRE45173, 143A

SMILES: Cc1ccncc1N1CCN(C1=O)c1ccc2c(N)nn(C)c2c1

InChI Key: InChIKey=JCUSTPJFYZIYLZ-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 132204   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cytochrome P450 17A1 (Homo sapiens (Human))	BDBM132204 (USRE45173, 143A) Show SMILES Cc1ccncc1N1CCN(C1=O)c1ccc2c(N)nn(C)c2c1 Show InChI InChI=1S/C17H18N6O/c1-11-5-6-19-10-15(11)23-8-7-22(17(23)24)12-3-4-13-14(9-12)21(2)20-16(13)18/h3-6,9-10H,7-8H2,1-2H3,(H2,18,20)	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	116	n/a	n/a	n/a	n/a	n/a	n/a
Novartis AG US Patent					Assay Description Cytochrome P450, 17-20 lyase (CYP17-lyase) assay development using recombinant human CYP17 enzyme and 17-alpha -hydroxy pregnenolone [21-3H] as the s...				US Patent USRE45173 (2014) BindingDB Entry DOI: 10.7270/Q2MW2FT2
					More data for this Ligand-Target Pair