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SMILES: Cc1ccncc1N1CCN(C1=O)c1ccnc(c1)C(F)(F)F

InChI Key: InChIKey=SHMNSOZXGJVYAJ-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 132209   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Steroid 17-alpha-hydroxylase/17,20 lyase


(Homo sapiens (Human))		BDBM132209
PNG
(USRE45173, 148A)
Show SMILES Cc1ccncc1N1CCN(C1=O)c1ccnc(c1)C(F)(F)F
Show InChI InChI=1S/C15H13F3N4O/c1-10-2-4-19-9-12(10)22-7-6-21(14(22)23)11-3-5-20-13(8-11)15(16,17)18/h2-5,8-9H,6-7H2,1H3
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Similars
US Patent
n/an/a 25n/an/an/an/an/an/a



Novartis AG

US Patent


Assay Description
Cytochrome P450, 17-20 lyase (CYP17-lyase) assay development using recombinant human CYP17 enzyme and 17-alpha -hydroxy pregnenolone [21-3H] as the s...

US Patent USRE45173 (2014)


BindingDB Entry DOI: 10.7270/Q2MW2FT2
More data for this
Ligand-Target Pair