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SMILES: Cc1ccncc1N1C(=O)N(CC1(C)C)c1ccc2ncsc2c1

InChI Key: InChIKey=WHUMCYYKWPLBAD-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 132226   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Steroid 17-alpha-hydroxylase/17,20 lyase (Homo sapiens (Human))	BDBM132226 (USRE45173, 165A | USRE45173, 202A) Show SMILES Cc1ccncc1N1C(=O)N(CC1(C)C)c1ccc2ncsc2c1 Show InChI InChI=1S/C18H18N4OS/c1-12-6-7-19-9-15(12)22-17(23)21(10-18(22,2)3)13-4-5-14-16(8-13)24-11-20-14/h4-9,11H,10H2,1-3H3	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	1.15E+3	n/a	n/a	n/a	n/a	n/a	n/a
Novartis AG US Patent					Assay Description Cytochrome P450, 17-20 lyase (CYP17-lyase) assay development using recombinant human CYP17 enzyme and 17-alpha -hydroxy pregnenolone [21-3H] as the s...				US Patent USRE45173 (2014) BindingDB Entry DOI: 10.7270/Q2MW2FT2
					More data for this Ligand-Target Pair
Steroid 17-alpha-hydroxylase/17,20 lyase (Homo sapiens (Human))	BDBM132226 (USRE45173, 165A | USRE45173, 202A) Show SMILES Cc1ccncc1N1C(=O)N(CC1(C)C)c1ccc2ncsc2c1 Show InChI InChI=1S/C18H18N4OS/c1-12-6-7-19-9-15(12)22-17(23)21(10-18(22,2)3)13-4-5-14-16(8-13)24-11-20-14/h4-9,11H,10H2,1-3H3	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	1.15E+3	n/a	n/a	n/a	n/a	n/a	n/a
Novartis AG US Patent					Assay Description Cytochrome P450, 17-20 lyase (CYP17-lyase) assay development using recombinant human CYP17 enzyme and 17-alpha -hydroxy pregnenolone [21-3H] as the s...				US Patent USRE45173 (2014) BindingDB Entry DOI: 10.7270/Q2MW2FT2
					More data for this Ligand-Target Pair