BDBM13366 (2S)-2-[(2R)-2-[(2S)-2-[(2R)-2-amino-3-sulfanylpropanamido]-3-methylbutanamido]-3-(4-hydroxy-2-methylphenyl)propanamido]-4-(methylsulfanyl)butanoic acid::CAAX Analogue 9::Compound IX

SMILES: CSCC[C@H](NC(=O)[C@@H](Cc1ccc(O)cc1C)NC(=O)[C@@H](NC(=O)[C@@H](N)CS)C(C)C)C(O)=O

InChI Key: InChIKey=QQGOSADBYFWSRS-OKYOBFRVSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 13366   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Protein farnesyltransferase (Bos taurus (bovine))	BDBM13366 ((2S)-2-[(2R)-2-[(2S)-2-[(2R)-2-amino-3-sulfanylpro...) Show SMILES CSCC[C@H](NC(=O)[C@@H](Cc1ccc(O)cc1C)NC(=O)[C@@H](NC(=O)[C@@H](N)CS)C(C)C)C(O)=O |r| Show InChI InChI=1S/C23H36N4O6S2/c1-12(2)19(27-20(29)16(24)11-34)22(31)26-18(10-14-5-6-15(28)9-13(14)3)21(30)25-17(23(32)33)7-8-35-4/h5-6,9,12,16-19,28,34H,7-8,10-11,24H2,1-4H3,(H,25,30)(H,26,31)(H,27,29)(H,32,33)/t16-,17-,18+,19-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.14E+4	n/a	n/a	n/a	n/a	7.5	37
Universita di Napoli Federico II					Assay Description Assays for PFT activity were performed with a PFT-specific scintillation assay (SPA) kit (Amersham Biosciences, Piscataway, NJ). IC50 values were cal...				J Med Chem 49: 1882-90 (2006) Article DOI: 10.1021/jm0506165 BindingDB Entry DOI: 10.7270/Q22V2DCH
					More data for this Ligand-Target Pair