BDBM134501 US8846656, 19-AH

SMILES: CO[C@@H]1CCN(C[C@H]1C)c1nc(nc2CCN(Cc12)c1cc(ccc1C)C(C)C)-c1c(C)cccc1Cl

InChI Key: InChIKey=JHDPPJOJWOHMET-SKCUWOTOSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 134501   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
C5a anaphylatoxin chemotactic receptor 1 (Homo sapiens (Human))	BDBM134501 (US8846656, 19-AH) Show SMILES CO[C@@H]1CCN(C[C@H]1C)c1nc(nc2CCN(Cc12)c1cc(ccc1C)C(C)C)-c1c(C)cccc1Cl |r| Show InChI InChI=1S/C31H39ClN4O/c1-19(2)23-11-10-20(3)27(16-23)35-14-12-26-24(18-35)31(36-15-13-28(37-6)22(5)17-36)34-30(33-26)29-21(4)8-7-9-25(29)32/h7-11,16,19,22,28H,12-15,17-18H2,1-6H3/t22-,28-/m1/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
Novartis AG US Patent					Assay Description Compounds were tested for their ability to inhibit C5a-mediated calcium mobilization using a stable cell line over expressing the human C5aR & the Ga...				US Patent US8846656 (2014) BindingDB Entry DOI: 10.7270/Q2JW8CKR
					More data for this Ligand-Target Pair