BDBM135634 US10179804, Example 19::US10632171, Peptide No. 19::US8846601, 19::US9458201, 19
SMILES: CC(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@H]1CC(=O)NCCCC[C@H](NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H](Cc2cccc3ccccc23)NC(=O)[C@H](Cc2c[nH]cn2)NC1=O)C(N)=O
InChI Key:
Data: 4 KI
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Melanocortin receptor 4 (Homo sapiens (Human)) | BDBM135634 (US10179804, Example 19 | US10632171, Peptide No. 1...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | 3 | n/a | n/a | n/a | n/a | n/a | n/a | 7.5 | n/a |
Palatin Technologies, Inc. US Patent | Assay Description A competitive inhibition binding assay is performed using membrane homogenates prepared from HEK-293 cells that express recombinant hMC4-R, hMC3-R, o... | US Patent US8846601 (2014) BindingDB Entry DOI: 10.7270/Q2SF2TWK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Melanocortin receptor 4 (Homo sapiens (Human)) | BDBM135634 (US10179804, Example 19 | US10632171, Peptide No. 1...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | 3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Palatin Technologies, Inc. US Patent | Assay Description A competitive inhibition binding assay is performed using membrane homogenates prepared from HEK-293 cells that express recombinant hMC4-R, hMC3-R, o... | US Patent US10632171 (2020) | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Melanocortin receptor 4 (Homo sapiens (Human)) | BDBM135634 (US10179804, Example 19 | US10632171, Peptide No. 1...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | 3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Palatin Technologies, Inc. US Patent | Assay Description Accumulation of intracellular cAMP was examined as a measure of the ability of the peptides of the present invention to elicit a functional response ... | US Patent US10179804 (2019) BindingDB Entry DOI: 10.7270/Q24T6MFP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Melanocortin receptor 4 (Homo sapiens (Human)) | BDBM135634 (US10179804, Example 19 | US10632171, Peptide No. 1...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | 3 | -12.1 | n/a | n/a | n/a | n/a | n/a | 7.5 | 37 |
Palatin Technologies, Inc. US Patent | Assay Description A competitive inhibition binding assay is performed using membrane homogenates prepared from HEK-293 cells that express recombinant hMC4-R, hMC3-R, o... | US Patent US9458201 (2016) BindingDB Entry DOI: 10.7270/Q2HT2N79 | |||||||||||
More data for this Ligand-Target Pair |