BDBM135882 US8859596, 169
SMILES: CCCCn1nc(s\c1=N/C(=O)c1cc(ccc1ONC(=O)C(C)(C)C)C(F)(F)F)C(C)(C)C
InChI Key: InChIKey=PGQIPALFIXUZFR-OOAXWGSJSA-N
Data: 2 KI
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Cannabinoid receptor 2 (Rattus norvegicus (Rat)) | BDBM135882 (US8859596, 169) | KEGG UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | 0.600 | n/a | n/a | n/a | n/a | n/a | n/a | 7.4 | n/a |
AbbVie Inc. US Patent | Assay Description HEK293 cells stably expressing rat CB2 receptors were grown until a confluent monolayer was formed. Briefly, the cells were harvested and homogenized... | US Patent US8859596 (2014) BindingDB Entry DOI: 10.7270/Q2W66JHC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cannabinoid receptor 2 (Homo sapiens (Human)) | BDBM135882 (US8859596, 169) | PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | 0.600 | -12.8 | n/a | n/a | n/a | n/a | n/a | 7.4 | 30 |
AbbVie Inc. US Patent | Assay Description HEK293 cells stably expressing human CB2 receptors were grown until a confluent monolayer was formed. Briefly, the cells were harvested and homogeniz... | US Patent US8859596 (2014) BindingDB Entry DOI: 10.7270/Q2W66JHC | |||||||||||
More data for this Ligand-Target Pair |