BDBM136298 US8853212, DDP-4 Inhibitor 14

SMILES: N[C@H]1C[C@H](CSC1c1cc(F)ccc1F)N1Cc2nc([nH]c2C1)-c1ccccc1

InChI Key:

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 136298   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Dipeptidyl peptidase 4 (Homo sapiens (Human))	BDBM136298 (US8853212, DDP-4 Inhibitor 14) Show SMILES N[C@H]1C[C@H](CSC1c1cc(F)ccc1F)N1Cc2nc([nH]c2C1)-c1ccccc1 |r| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	0.700	n/a	n/a	n/a	n/a	7.5	n/a
Merck Sharp & Dohme Corp US Patent					Assay Description A continuous fluorometric assay is employed with the substrate Gly-Pro-AMC, which is cleaved by DPP-4 to release the fluorescent AMC leaving group. T...				US Patent US8853212 (2014) BindingDB Entry DOI: 10.7270/Q2C53JK4
					More data for this Ligand-Target Pair