BDBM13669 2-bromo-3-[2-(2,4-dichlorophenyl)ethoxy]-5-({[1-(pyridin-4-yl)piperidin-4-yl]methyl}carbamoyl)phenyl acetate::3-Oxybenzamide 55

SMILES: CC(=O)Oc1cc(cc(OCCc2ccc(Cl)cc2Cl)c1Br)C(=O)NCC1CCN(CC1)c1ccncc1

InChI Key: InChIKey=AFXSBHYPZXEQNT-UHFFFAOYSA-N

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 13669   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Coagulation factor X (Homo sapiens (Human))	BDBM13669 (2-bromo-3-[2-(2,4-dichlorophenyl)ethoxy]-5-({[1-(p...) Show SMILES CC(=O)Oc1cc(cc(OCCc2ccc(Cl)cc2Cl)c1Br)C(=O)NCC1CCN(CC1)c1ccncc1 Show InChI InChI=1S/C28H28BrCl2N3O4/c1-18(35)38-26-15-21(14-25(27(26)29)37-13-8-20-2-3-22(30)16-24(20)31)28(36)33-17-19-6-11-34(12-7-19)23-4-9-32-10-5-23/h2-5,9-10,14-16,19H,6-8,11-13,17H2,1H3,(H,33,36)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	285	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Sanofi-Aventis Deutschland GmbH Curated by ChEMBL					Assay Description Binding affinity to human factor 10a using S-2765 as substrate preincubated for 15 mins followed by substrate addition measured between 1 and 5 mins ...				Bioorg Med Chem Lett 28: 2343-2352 (2018) Article DOI: 10.1016/j.bmcl.2018.05.061 BindingDB Entry DOI: 10.7270/Q28918HM
					More data for this Ligand-Target Pair
Coagulation factor X (Homo sapiens (Human))	BDBM13669 (2-bromo-3-[2-(2,4-dichlorophenyl)ethoxy]-5-({[1-(p...) Show SMILES CC(=O)Oc1cc(cc(OCCc2ccc(Cl)cc2Cl)c1Br)C(=O)NCC1CCN(CC1)c1ccncc1 Show InChI InChI=1S/C28H28BrCl2N3O4/c1-18(35)38-26-15-21(14-25(27(26)29)37-13-8-20-2-3-22(30)16-24(20)31)28(36)33-17-19-6-11-34(12-7-19)23-4-9-32-10-5-23/h2-5,9-10,14-16,19H,6-8,11-13,17H2,1H3,(H,33,36)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	285	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Aventis Pharma Deutschland GmbH					Assay Description The inhibitory effect of test compound for human fXa was determined by using the chromogenic substrates S-2765. The hydrolysis rates of chromogenic s...				J Med Chem 48: 3290-312 (2005) Article DOI: 10.1021/jm049187l BindingDB Entry DOI: 10.7270/Q28C9THZ
					More data for this Ligand-Target Pair