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SMILES: CC(C)Nc1ccc(cn1)C(=O)Nc1cc(ccc1C)C(=O)N1CCC(CC1)c1ccc(cn1)C#N

InChI Key: InChIKey=XEZUISUJZIASNT-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 136985   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Fatty acid synthase


(Homo sapiens (Human))		BDBM136985
PNG
(US8871790, 50)
Show SMILES CC(C)Nc1ccc(cn1)C(=O)Nc1cc(ccc1C)C(=O)N1CCC(CC1)c1ccc(cn1)C#N
Show InChI InChI=1S/C28H30N6O2/c1-18(2)32-26-9-7-23(17-31-26)27(35)33-25-14-22(6-4-19(25)3)28(36)34-12-10-21(11-13-34)24-8-5-20(15-29)16-30-24/h4-9,14,16-18,21H,10-13H2,1-3H3,(H,31,32)(H,33,35)
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MMDB

KEGG

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Similars
US Patent
n/an/a 520n/an/an/an/an/an/a



3-V Biosciences, Inc.

US Patent


Assay Description
The FASN enzyme was isolated from SKBr3 cells. SKBr3 is a human breast cancer cell-line with high levels of FASN expression. It is estimated that FAS...

US Patent US8871790 (2014)


BindingDB Entry DOI: 10.7270/Q2PG1QD3
More data for this
Ligand-Target Pair