BDBM136990 US8871790, 55

SMILES: CCc1ccc(cc1NC(=O)c1ccc(nc1)N1CCC1)C(=O)N1CCC(F)(CC1)c1ccc(cc1)C#N

InChI Key: InChIKey=DHBZNEAWYSUACT-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 136990   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Fatty acid synthase (Homo sapiens (Human))	BDBM136990 (US8871790, 55) Show SMILES CCc1ccc(cc1NC(=O)c1ccc(nc1)N1CCC1)C(=O)N1CCC(F)(CC1)c1ccc(cc1)C#N Show InChI InChI=1S/C30H30FN5O2/c1-2-22-6-7-23(18-26(22)34-28(37)24-8-11-27(33-20-24)35-14-3-15-35)29(38)36-16-12-30(31,13-17-36)25-9-4-21(19-32)5-10-25/h4-11,18,20H,2-3,12-17H2,1H3,(H,34,37)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	35	n/a	n/a	n/a	n/a	n/a	n/a
3-V Biosciences, Inc. US Patent					Assay Description The FASN enzyme was isolated from SKBr3 cells. SKBr3 is a human breast cancer cell-line with high levels of FASN expression. It is estimated that FAS...				US Patent US8871790 (2014) BindingDB Entry DOI: 10.7270/Q2PG1QD3
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