BDBM137012 US8871790, 78

SMILES: Cc1ccc(cc1NC(=O)NC[C@H]1CCCO1)C(=O)N1CCC(F)(CC1)c1ccc(cc1)C#N

InChI Key: InChIKey=IQCRKWMWEVJSMV-JOCHJYFZSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 137012   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Fatty acid synthase (Homo sapiens (Human))	BDBM137012 (US8871790, 78) Show SMILES Cc1ccc(cc1NC(=O)NC[C@H]1CCCO1)C(=O)N1CCC(F)(CC1)c1ccc(cc1)C#N |r| Show InChI InChI=1S/C26H29FN4O3/c1-18-4-7-20(15-23(18)30-25(33)29-17-22-3-2-14-34-22)24(32)31-12-10-26(27,11-13-31)21-8-5-19(16-28)6-9-21/h4-9,15,22H,2-3,10-14,17H2,1H3,(H2,29,30,33)/t22-/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	35	n/a	n/a	n/a	n/a	n/a	n/a
3-V Biosciences, Inc. US Patent					Assay Description The FASN enzyme was isolated from SKBr3 cells. SKBr3 is a human breast cancer cell-line with high levels of FASN expression. It is estimated that FAS...				US Patent US8871790 (2014) BindingDB Entry DOI: 10.7270/Q2PG1QD3
					More data for this Ligand-Target Pair