BDBM13707 1-({3-[2-(2,4-dichlorophenyl)ethoxy]-4-ethoxyphenyl}carbonyl)-4-(pyridin-4-ylmethyl)piperazine::3-Oxybenzamide 93

SMILES: CCOc1ccc(cc1OCCc1ccc(Cl)cc1Cl)C(=O)N1CCN(Cc2ccncc2)CC1

InChI Key: InChIKey=IIIZKJYRBVJHEI-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 13707   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Coagulation factor X (Homo sapiens (Human))	BDBM13707 (1-({3-[2-(2,4-dichlorophenyl)ethoxy]-4-ethoxypheny...) Show SMILES CCOc1ccc(cc1OCCc1ccc(Cl)cc1Cl)C(=O)N1CCN(Cc2ccncc2)CC1 Show InChI InChI=1S/C27H29Cl2N3O3/c1-2-34-25-6-4-22(17-26(25)35-16-9-21-3-5-23(28)18-24(21)29)27(33)32-14-12-31(13-15-32)19-20-7-10-30-11-8-20/h3-8,10-11,17-18H,2,9,12-16,19H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	306	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Aventis Pharma Deutschland GmbH					Assay Description The inhibitory effect of test compound for human fXa was determined by using the chromogenic substrates S-2765. The hydrolysis rates of chromogenic s...				J Med Chem 48: 3290-312 (2005) Article DOI: 10.1021/jm049187l BindingDB Entry DOI: 10.7270/Q28C9THZ
					More data for this Ligand-Target Pair