BDBM137225 US8871790, 297

SMILES: CC(C)CNC(=O)Nc1cc(ccc1C)C(=O)N1CCC(F)(CC1)c1ccc(cc1)C#N

InChI Key: InChIKey=AWGLLQHLDDCYEK-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 137225   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Fatty acid synthase (Homo sapiens (Human))	BDBM137225 (US8871790, 297) Show SMILES CC(C)CNC(=O)Nc1cc(ccc1C)C(=O)N1CCC(F)(CC1)c1ccc(cc1)C#N Show InChI InChI=1S/C25H29FN4O2/c1-17(2)16-28-24(32)29-22-14-20(7-4-18(22)3)23(31)30-12-10-25(26,11-13-30)21-8-5-19(15-27)6-9-21/h4-9,14,17H,10-13,16H2,1-3H3,(H2,28,29,32)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	25	n/a	n/a	n/a	n/a	n/a	n/a
3-V Biosciences, Inc. US Patent					Assay Description The FASN enzyme was isolated from SKBr3 cells. SKBr3 is a human breast cancer cell-line with high levels of FASN expression. It is estimated that FAS...				US Patent US8871790 (2014) BindingDB Entry DOI: 10.7270/Q2PG1QD3
					More data for this Ligand-Target Pair