BDBM137233 US8871790, 312

SMILES: Cc1ccc(cc1NC(=O)c1ccc(nc1)N1CCC1)C(=O)N1CCC(F)(CC1)c1ccc(cc1)C#N

InChI Key: InChIKey=VPTDZYLGBLPQHQ-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 137233   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Fatty acid synthase (Homo sapiens (Human))	BDBM137233 (US8871790, 312) Show SMILES Cc1ccc(cc1NC(=O)c1ccc(nc1)N1CCC1)C(=O)N1CCC(F)(CC1)c1ccc(cc1)C#N Show InChI InChI=1S/C29H28FN5O2/c1-20-3-6-22(17-25(20)33-27(36)23-7-10-26(32-19-23)34-13-2-14-34)28(37)35-15-11-29(30,12-16-35)24-8-4-21(18-31)5-9-24/h3-10,17,19H,2,11-16H2,1H3,(H,33,36)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	25	n/a	n/a	n/a	n/a	n/a	n/a
3-V Biosciences, Inc. US Patent					Assay Description The FASN enzyme was isolated from SKBr3 cells. SKBr3 is a human breast cancer cell-line with high levels of FASN expression. It is estimated that FAS...				US Patent US8871790 (2014) BindingDB Entry DOI: 10.7270/Q2PG1QD3
					More data for this Ligand-Target Pair