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BDBM137312 US8871790, 398

SMILES: CCc1cc(C)c(cc1-c1nc2CCN(Cc2[nH]1)C(C)=O)C(=O)N1CCC(CC1)c1ccc(cc1)C#N

InChI Key: InChIKey=ATVSNQSBQVWDNK-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 137312   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Fatty acid synthase


(Homo sapiens (Human))
BDBM137312
PNG
(US8871790, 398)
Show SMILES CCc1cc(C)c(cc1-c1nc2CCN(Cc2[nH]1)C(C)=O)C(=O)N1CCC(CC1)c1ccc(cc1)C#N
Show InChI InChI=1S/C30H33N5O2/c1-4-22-15-19(2)25(16-26(22)29-32-27-11-14-35(20(3)36)18-28(27)33-29)30(37)34-12-9-24(10-13-34)23-7-5-21(17-31)6-8-23/h5-8,15-16,24H,4,9-14,18H2,1-3H3,(H,32,33)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

US Patent
n/an/a 35n/an/an/an/an/an/a



3-V Biosciences, Inc.

US Patent


Assay Description
The FASN enzyme was isolated from SKBr3 cells. SKBr3 is a human breast cancer cell-line with high levels of FASN expression. It is estimated that FAS...


US Patent US8871790 (2014)


BindingDB Entry DOI: 10.7270/Q2PG1QD3
More data for this
Ligand-Target Pair