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SMILES: CN1CCc2[nH]c(nc2C1)-c1cc(C(=O)N2CCC(CC2)c2ccc(cc2)C#N)c(C)cc1C

InChI Key: InChIKey=VLZCNNXPAXQXGU-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 137339   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Fatty acid synthase


(Homo sapiens (Human))		BDBM137339
PNG
(US8871790, 425)
Show SMILES CN1CCc2[nH]c(nc2C1)-c1cc(C(=O)N2CCC(CC2)c2ccc(cc2)C#N)c(C)cc1C
Show InChI InChI=1S/C28H31N5O/c1-18-14-19(2)24(15-23(18)27-30-25-10-11-32(3)17-26(25)31-27)28(34)33-12-8-22(9-13-33)21-6-4-20(16-29)5-7-21/h4-7,14-15,22H,8-13,17H2,1-3H3,(H,30,31)
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Similars
US Patent
n/an/a 75n/an/an/an/an/an/a



3-V Biosciences, Inc.

US Patent


Assay Description
The FASN enzyme was isolated from SKBr3 cells. SKBr3 is a human breast cancer cell-line with high levels of FASN expression. It is estimated that FAS...

US Patent US8871790 (2014)


BindingDB Entry DOI: 10.7270/Q2PG1QD3
More data for this
Ligand-Target Pair