BDBM137358 US8871790, 444

SMILES: FC1(CCN(CC1)C(=O)c1ccc(C2CCC2)c(NC(=O)N[C@H]2CCOC2)c1)c1ccc(cc1)C#N

InChI Key: InChIKey=GCBYFMLJKXJBDZ-QHCPKHFHSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 137358   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Fatty acid synthase (Homo sapiens (Human))	BDBM137358 (US8871790, 444) Show SMILES FC1(CCN(CC1)C(=O)c1ccc(C2CCC2)c(NC(=O)N[C@H]2CCOC2)c1)c1ccc(cc1)C#N |r| Show InChI InChI=1S/C28H31FN4O3/c29-28(22-7-4-19(17-30)5-8-22)11-13-33(14-12-28)26(34)21-6-9-24(20-2-1-3-20)25(16-21)32-27(35)31-23-10-15-36-18-23/h4-9,16,20,23H,1-3,10-15,18H2,(H2,31,32,35)/t23-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	40	n/a	n/a	n/a	n/a	n/a	n/a
3-V Biosciences, Inc. US Patent					Assay Description The FASN enzyme was isolated from SKBr3 cells. SKBr3 is a human breast cancer cell-line with high levels of FASN expression. It is estimated that FAS...				US Patent US8871790 (2014) BindingDB Entry DOI: 10.7270/Q2PG1QD3
					More data for this Ligand-Target Pair