BDBM13780 2-(3-{5-amino-1H-imidazo[4,5-b]pyridin-2-yl}-4-hydroxy-5-(3-nitrophenyl)phenyl)acetic acid::imidazopyridine analog 4
SMILES: Nc1ccc2[nH]c(nc2n1)-c1cc(CC(O)=O)cc(-c2cccc(c2)[N+]([O-])=O)c1O
InChI Key: InChIKey=FIJGUBVGCGLGJQ-UHFFFAOYSA-N
Data: 4 KI
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Coagulation factor VII (Homo sapiens (Human)) | BDBM13780 (2-(3-{5-amino-1H-imidazo[4,5-b]pyridin-2-yl}-4-hyd...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 3.90E+4 | -5.95 | n/a | n/a | n/a | n/a | n/a | 7.4 | 22 |
Celera | Assay Description The enzyme reactions were initiated by the addition of substrate, and the color developed from the release of p-nitroanilide from each chromogenic su... | Bioorg Med Chem Lett 16: 2270-3 (2006) Article DOI: 10.1016/j.bmcl.2006.01.017 BindingDB Entry DOI: 10.7270/Q2RF5S8X | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prothrombin (Homo sapiens (Human)) | BDBM13780 (2-(3-{5-amino-1H-imidazo[4,5-b]pyridin-2-yl}-4-hyd...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | >1.50E+5 | >-5.16 | n/a | n/a | n/a | n/a | n/a | 7.4 | 22 |
Celera | Assay Description The enzyme reactions were initiated by the addition of substrate, and the color developed from the release of p-nitroanilide from each chromogenic su... | Bioorg Med Chem Lett 16: 2270-3 (2006) Article DOI: 10.1016/j.bmcl.2006.01.017 BindingDB Entry DOI: 10.7270/Q2RF5S8X | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serine protease 1 (Bos taurus (bovine)) | BDBM13780 (2-(3-{5-amino-1H-imidazo[4,5-b]pyridin-2-yl}-4-hyd...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | >1.50E+5 | >-5.16 | n/a | n/a | n/a | n/a | n/a | 7.4 | 22 |
Celera | Assay Description The enzyme reactions were initiated by the addition of substrate, and the color developed from the release of p-nitroanilide from each chromogenic su... | Bioorg Med Chem Lett 16: 2270-3 (2006) Article DOI: 10.1016/j.bmcl.2006.01.017 BindingDB Entry DOI: 10.7270/Q2RF5S8X | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Coagulation factor X (Homo sapiens (Human)) | BDBM13780 (2-(3-{5-amino-1H-imidazo[4,5-b]pyridin-2-yl}-4-hyd...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | >1.50E+5 | >-5.16 | n/a | n/a | n/a | n/a | n/a | 7.4 | 22 |
Celera | Assay Description The enzyme reactions were initiated by the addition of substrate, and the color developed from the release of p-nitroanilide from each chromogenic su... | Bioorg Med Chem Lett 16: 2270-3 (2006) Article DOI: 10.1016/j.bmcl.2006.01.017 BindingDB Entry DOI: 10.7270/Q2RF5S8X | |||||||||||
More data for this Ligand-Target Pair |