BDBM138122 US8871783, 8

SMILES: CN1C(=O)Cc2ccc(cc12)-c1ccc2oc(CC(NC(=O)[C@H]3N[C@@H]4CC[C@H]3C4)C#N)cc2c1

InChI Key: InChIKey=BSKPTJIGROLSFG-IQECEXMCSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 138122   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Dipeptidyl peptidase I (Homo sapiens (Human))	BDBM138122 (US8871783, 8) Show SMILES CN1C(=O)Cc2ccc(cc12)-c1ccc2oc(CC(NC(=O)[C@H]3N[C@@H]4CC[C@H]3C4)C#N)cc2c1 |r| Show InChI InChI=1S/C27H26N4O3/c1-31-23-11-16(2-3-17(23)12-25(31)32)15-5-7-24-19(8-15)10-22(34-24)13-21(14-28)30-27(33)26-18-4-6-20(9-18)29-26/h2-3,5,7-8,10-11,18,20-21,26,29H,4,6,9,12-13H2,1H3,(H,30,33)/t18-,20+,21?,26-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	104	-9.52	n/a	n/a	n/a	n/a	n/a	6.0	25
Boehringer Ingelheim International GmBh US Patent					Assay Description The following buffers were used: MES buffer: 25 mM MES, 50 mM NaCl, 5 mM DTT, adjusted to pH 6.0, containing 0.1% BSA; TAGZyme Buffer: 20 mM NaH2PO4,...				US Patent US8871783 (2014) BindingDB Entry DOI: 10.7270/Q2F18XF1
					More data for this Ligand-Target Pair